HRID869664

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID582305

5-Chloropyridin-3-ol

C5H4ClNO

HCID15080989

Ethyl 3-hydroxypyridine-2-carboxylate

C8H9NO3

结构：CC(C)(C)OC(=O)N1C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@@H]1CO

HCID66962096

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)c1ncccc1OC[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C

HCID66962085

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in Step 1 of EXAMPLE 29 using (2R,4S)-tert-butyl 4-((tert-butyldimethylsilyl)oxy)-2-(hydroxymethyl)pyrrolidine-1-carboxylate (PCT Int. Appl., WO2009026197) and ethyl 3-hydroxypicolinate instead of (R)-pyrrolidin-2-ylmethanol and 5-chloropyridin-3-ol.