HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxy-5-chloropyridine → Ethyl 3-((1-(tert-butoxycarbonyl)-3-methylpyrrolidin-3-yl)methoxy)picolinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxy-5-chloropyridine | HCID 582305 | — |
| Reactant | Ethyl 3-hydroxypicolinate | HCID 15080989 | — |
| Reactant | 1-Boc-3-methylpyrrolidine-3-methanol | HCID 59708456 | — |
| Product | Ethyl 3-((1-(tert-butoxycarbonyl)-3-methylpyrrolidin-3-yl)methoxy)picolinate | HCID 66962165 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Step 1 of EXAMPLE 29 using tert-butyl 3-(hydroxymethyl)-3-methylpyrrolidine-1-carboxylate and ethyl 3-hydroxypicolinate instead of (R)-tert-butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate and 5-chloropyridin-3-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969383B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-9defc98024be4d2a8def6ff1ac2475c5 |
| Source note | uspto-grants-2015_03 |