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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 869671Generated: October 30, 2026

3-Hydroxy-5-chloropyridine → HCID 66961874, compound

https://huagongshe.com/reaction/869671

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxy-5-chloropyridineHCID 582305—
Reactanttert-Butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylateHCID 5237175—
ReactantEthyl 3-hydroxypicolinateHCID 15080989—
ProductHCID 66961874HCID 66961874—

Reaction Steps

The title compound was prepared according to the procedure described in Step 1 of EXAMPLE 29 using tert-butyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate and ethyl 3-hydroxypicolinate instead of (R)-tert-butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate and 5-chloropyridin-3-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969383B2
Source datasetuspto-grants-2015_03
ORD IDord-794e066f98e2494f9c6ef9f30937b436
Source noteuspto-grants-2015_03