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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 869672Generated: October 30, 2026

Indole-2-carboxylic acid → HCID 178470236, compound

https://huagongshe.com/reaction/869672

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-2-carboxylic acidHCID 72899—
ReactantEthyl 3-(pyrrolidin-3-ylmethoxy)picolinateHCID 66962066—
ReactantHCID 178525710HCID 178525710—
ProductHCID 178470236HCID 178470236—

Reaction Steps

The title compound was prepared according to the procedure described in Step 3 of EXAMPLE 1 using ethyl 3-(pyrrolidin-3-ylmethoxy)picolinate (EXAMPLE 92, Step 2) and trans-4-(trifluoromethyl)cyclohexanecarboxylic acid instead of (R)-3-(pyrrolidin-2-ylmethoxy)picolinamide dihydrochloride and indole-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969383B2
Source datasetuspto-grants-2015_03
ORD IDord-7c40f4c62b24445b9b57ea3cb9bd5d29
Source noteuspto-grants-2015_03