HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-(((tert-butoxy)carbonyl)amino)pentanoic acid → methyl N-(tert-butoxycarbonyl)-L-norvalyl-L-threoninate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-(((tert-butoxy)carbonyl)amino)pentanoic acid | HCID 2733748 | — |
| Reactant | Ethyl L-threoninate hydrochloride | HCID 2763096 | — |
| Product | methyl N-(tert-butoxycarbonyl)-L-norvalyl-L-threoninate | HCID 86674524 | — |
Reaction Steps
The preparation was performed in a similar manner as Example 1.001 (d) Method B from N-(tert-butoxycarbonyl)-L-norvaline (13.0 g, 59.8 mmol) and L-threonine ethyl ester hydrochloride (9.23 g, 54.4 mmol) to give methyl N-(tert-butoxycarbonyl)-L-norvalyl-L-threoninate. MS (APCI): m/z 333 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969376B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-d0aaed4f417b4af3917ef0ff3b95f332 |
| Source note | uspto-grants-2015_03 |