HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 4-(3-Chlorobenzyl)thiophene-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 3-Bromo-4-(3-chlorobenzyl)thiophene | HCID 45140581 | — |
| Product | 4-(3-Chlorobenzyl)thiophene-3-carboxylic acid | HCID 45140589 | — |
Reaction Steps
3-Bromo-4-(3-chlorobenzyl)thiophene from Example 3, Step 2 (6.22 g, 21.6 mmol) was reacted under conditions similar to Example 1, Step 6 (Et2O was used as a solvent instead of THF), to afford the desired product as an off-white solid that was used directly without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969394B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-c9bb23e6a2bd450c87babcefdd9727ae |
| Source note | uspto-grants-2015_03 |