HCID 86613976, compound → HCID 11348242, compound

HRID 870074Notes

Reaction equation

HRID 870074 reaction equation
[CH3:1][N:2]([CH3:29])[C:3]1[CH:8]=[CH:7][C:6]([S:9]([N:12]2[CH:16]=[CH:15][C:14](/[CH:17]=[CH:18]/[C:19]([NH:21][O:22]C3CCCCO3)=[O:20])=[CH:13]2)(=[O:11])=[O:10])=[CH:5][CH:4]=1>CO.O>[CH3:29][N:2]([CH3:1])[C:3]1[CH:4]=[CH:5][C:6]([S:9]([N:12]2[CH:16]=[CH:15][C:14](/[CH:17]=[CH:18]/[C:19]([NH:21][OH:22])=[O:20])=[CH:13]2)(=[O:10])=[O:11])=[CH:7][CH:8]=1

Participants

3

Reactant 1

HCID 86613976HCID 86613976, compound2×

Product 1

HCID 11348242HCID 11348242, compound

Reagents, catalysts & solvents 1

HCID 22242641Methanol--water (1/1)Solvent

Procedure

The method used for preparation of this compound is analogous to the method described for compound 2. Starting materials: (E)-3-[1-(4-dimethylamino-benzene sulfonyl)-1H-pyrrol-3-yl]-N-(tetrahydro-pyran-2-yloxy)-acrylamide (compound A4) (0200 g), methanol/water 3/2 (50 ml), amberlyst IR15 (0.402 g).

Workup

  1. customThe method used for preparation of this compound

Sources & evidence

ORD record
ord-1108a84d4a1d4d95b9c53a570a57a88b
Source dataset
uspto-grants-2015_03
Patent number
US08969401B2

Reaction notes

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