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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 870100Generated: October 28, 2026

m-Bromobenzenesulphonyl chloride → (E)-3-[1-(3-Bromo-benzenesulfonyl)-1H-pyrrol-3-yl]-acrylic acid tert-butyl ester

https://huagongshe.com/reaction/870100

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Bromobenzenesulphonyl chlorideHCID 17943—
Reactanttert-butyl (2E)-3-(1H-pyrrol-3-yl)prop-2-enoateHCID 66646340—
Product(E)-3-[1-(3-Bromo-benzenesulfonyl)-1H-pyrrol-3-yl]-acrylic acid tert-butyl esterHCID 66646069—

Reaction Steps

Starting from compound D1 and 3-bromo-benzenesulfonyl chloride the title compound can be obtained analogously as described for compound D4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969401B2
Source datasetuspto-grants-2015_03
ORD IDord-5cd278aaaeaf4ce7a7ebac535df636a8
Source noteuspto-grants-2015_03