Benzenemethanamine, 2,4-dichloro-N-methyl- → 3-(6,8-Dichloro-2-ethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzene-1-sulfonyl chloride
반응식
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[C:10]([Cl:12])[CH:11]=1)[CH2:8][N:7]([CH3:13])[CH2:6][CH:5]2[C:14]1[CH:15]=[C:16]([S:20]([Cl:23])(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1.Cl[C:25]1C=C(Cl)C=CC=1CNC>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[C:10]([Cl:12])[CH:11]=1)[CH2:8][N:7]([CH2:13][CH3:25])[CH2:6][CH:5]2[C:14]1[CH:15]=[C:16]([S:20]([Cl:23])(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1참가 물질
3
실험 절차
Using procedures outlined in Example 1 to prepare intermediate 1.6, substituting N-(2,4-dichlorobenzyl)ethanamine for 1-(2,4-dichlorophenyl)-N-methylmethanamine, the title compound was prepared as a hydrochloride salt.
출처 및 근거
- ORD 기록
- ord-3b4e550eb07246b8b029a2f777420982
- 출처 데이터셋
- uspto-grants-2015_03
- 특허 번호
- US08969377B2
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