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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 870338Generated: October 26, 2026

toluene-4-sulfonic acid (R)-2-phenylpropyl ester → ((R)-2-Fluoro-1-methyl-ethyl)-benzene

https://huagongshe.com/reaction/870338

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttoluene-4-sulfonic acid (R)-2-phenylpropyl esterHCID 13791929—
Reactant((S)-2-Fluoro-1-methyl-ethyl)-benzeneHCID 53628601—
Product((R)-2-Fluoro-1-methyl-ethyl)-benzeneHCID 53628603—

Reaction Steps

The title compound was prepared as described above for the synthesis of ((S)-2-fluoro-1-methyl-ethyl)-benzene, but using toluene-4-sulfonic acid (R)-2-phenyl-propyl ester instead of toluene-4-sulfonic acid (S)-2-phenyl-propyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969552B2
Source datasetuspto-grants-2015_03
ORD IDord-3f0e2b0585ee4ab68c67d57f521d76b0
Source noteuspto-grants-2015_03