Methanol → HCID 131732536, compound

Participants

Reaction Conditions

Reaction Steps

(7-Methoxy-chroman-3-yl)-propyl-amine (1.3 g, 5.87 mmol) was dissolved in dichloromethane (100 ml) and cooled to −78° C. Boron tribromide (11.7 ml, 122.52 mmol) was added and the reaction mixture was allowed to reach room temperature over night. The reaction mixture was cooled to −78° C. and a mixture of methanol and dichloromethane (2:3) was slowly added. The reaction mixture was allowed to reach room temperature and was then evaporated to dryness to yield the crude product (1.69 g, 5.86 mmol)

Provenance & Evidence