3-Buten-2-ol → HCID 66713418, compound

HRID 870550Notes

Reaction equation

HRID 870550 reaction equation
Cl[C:2]1[N:11]=[C:10]([C:12]2[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[C:14]([O:22][CH3:23])[CH:13]=2)[CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2.[CH3:24][CH:25]([OH:28])[CH:26]=[CH2:27]>>[CH3:24][CH:25]([O:28][C:2]1[N:11]=[C:10]([C:12]2[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[C:14]([O:22][CH3:23])[CH:13]=2)[CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2)[CH:26]=[CH2:27]

Participants

3

Reactant 2

HCID 117163-Buten-2-olHCID 58071863HCID 58071863, compound

Product 1

HCID 66713418HCID 66713418, compound

Procedure

5-(1-Methyl-allyloxy)-7-(3,4,5-trimethoxy-phenyl)-[1,6]naphthyridine (for Example 31) was prepared from 5-chloro-7-(3,4,5-trimethoxy-phenyl)-[1,6]naphthyridine and (R/S)-but-3-en-2-ol using an analogous procedure

Sources & evidence

ORD record
ord-5985bc4bf0b84c54b295e1f6f5b63e74
Source dataset
uspto-grants-2015_03
Patent number
US08969568B2

Reaction notes

Loading…