1,1'-Carbonyldiimidazole → N-pent-4-ynylimidazole-1-carboxamide

Beteiligte Stoffe

Reaktionsschritte

Add 1,1′-carbonyldiimidazole (0.539 mg 1.05 equiv; 3.26 mmoles) slowly portion wise to a −78° C. solution of 4-pentyn-1-amine (0.258 mL; 1.0 equiv; 3.10 mmoles) in dichloromethane (10 mL). Allow the reaction to warm to ambient temperature and stir for 72 hours. Use the solution directly for subsequent chemistry: MS (m/z): 178(M+1).

Herkunft & Nachweise