N-Methylbutylamine → HCID 86696357, compound

Participants

Reaction Steps

A neat solution of 3-bromo-6-chloro-imidazo[1,2-b]pyridazine [13526-66-4] (522.9 mg, 2.3 mmol) in N-methyl butylamine [110-68-9] (3.0 mL, 24.3 mmol) and Hunig's base [7087-68-5] (0.6 mL, 3.5 mmol) was stirred under N2 blanket at 65° C. overnight then evaporated to provide 0.9 g of yellow solid, used in the next step without further purification. LRMS (ESI) m/z 283.1/285.1 [(M+H)]+, calc'd for C11H15BrN4: 283.17.

Provenance & Evidence