4-Amino-2-methylbutan-2-ol → HCID 86696408, compound

HRID 870706Notes

Reaction equation

HRID 870706 reaction equation
[Br:1][C:2]1[N:6]2[N:7]=[C:8](F)[CH:9]=[CH:10][C:5]2=[N:4][CH:3]=1.[NH2:12][CH2:13][CH2:14][C:15]([CH3:18])([OH:17])[CH3:16]>>[Br:1][C:2]1[N:6]2[N:7]=[C:8]([NH:12][CH2:13][CH2:14][C:15]([CH3:18])([OH:17])[CH3:16])[CH:9]=[CH:10][C:5]2=[N:4][CH:3]=1

Participants

3

Reactant 2

HCID 156491734-Amino-2-methylbutan-2-olHCID 866963183-Bromo-6-fluoroimidazo[1,2-b]pyridazine

Product 1

HCID 86696408HCID 86696408, compoundYield 82%

Procedure

The 3-bromo-6-fluoroimidazo[1,2-b]pyridazine was reacted with 4-amino-2-methylbutan-2-ol using the same reaction conditions as described in example 5.6.42, Part A to obtain 82% product.

Workup

  1. customthe same reaction conditions

Sources & evidence

ORD record
ord-eb7eb12d38d64454b0a7918041451a35
Source dataset
uspto-grants-2015_03
Patent number
US08969565B2

Reaction notes

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