Ethyl trifluoroacetate → HCID 54438168, compound

Participants

Reaction Steps

Ethyl trifluoroacetate [383-63-1] (5.5 mL, 46.1 mmol) was added to a stirred, 0° C., solution of N1-phenylethane-1,2-diamine [1664-40-0] (5.0 mL, 38.4 mmol) in THF (125 mL) and was allowed to stir and warm to ambient temperature under N2 blanket over 17 h then was partitioned between brine and ethyl acetate. The extract was dried (MgSO4) and evaporated to provide 10.2 g of clear dark yellow liquid. LRMS (ESI) m/z 232.9 [(M+H)]+, calc'd for C10H11F3N2O: 232.21.

Provenance & Evidence