Acetone → 5-tert-Butoxycarbonylamino-3-(3-fluoro-4-nitro-benzyl)-4-oxo-tetrahydro-thiopyran-3-carboxylic acid allyl ester
Reaction equation
[Br:28][CH2:29][c:30]1[cH:31][c:32]([F:39])[c:33]([N+:36](=[O:37])[O-:38])[cH:34][cH:35]1.[CH2:1]([CH:2]=[CH2:3])[O:4][C:5](=[O:6])[CH:7]1[CH2:8][S:9][CH2:10][CH:11]([NH:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[C:12]1=[O:13].[CH3:40][C:41](=[O:42])[CH3:43].[K+:22].[K+:23].[O-:24][C:25]([O-:26])=[O:27]>>[CH2:1]([CH:2]=[CH2:3])[O:4][C:5](=[O:6])[C:7]1([CH2:29][c:30]2[cH:31][c:32]([F:39])[c:33]([N+:36](=[O:37])[O-:38])[cH:34][cH:35]2)[CH2:8][S:9][CH2:10][CH:11]([NH:14][C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[C:12]1=[O:13]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5b05077d1cab4e678cf9ac3d4b66f52c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…