Acetonitrile → 8-(1-{2-oxo-2-[5-oxo-1-(3-trifluoromethyl-phenyl)-pyrrolidin-3-yl]-ethyl}-1H-pyrazol-4-yl)-1,3-dipropyl-7-(2-trimethylsilanyl-ethoxymethyl)-3,7-dihydro-purine-2,6-dione
Reaction equation
[Br:31][CH2:32][C:33](=[O:34])[CH:35]1[CH2:36][C:37](=[O:50])[N:38]([c:40]2[cH:41][c:42]([C:46]([F:47])([F:48])[F:49])[cH:43][cH:44][cH:45]2)[CH2:39]1.[C:51](=[O:52])([O-:53])[O-:54].[CH2:1]([CH2:2][CH3:3])[n:4]1[c:5](=[O:30])[n:6]([CH2:27][CH2:28][CH3:29])[c:7]2[n:8][c:9](-[c:22]3[cH:23][n:24][nH:25][cH:26]3)[n:10]([CH2:14][O:15][CH2:16][CH2:17][Si:18]([CH3:19])([CH3:20])[CH3:21])[c:11]2[c:12]1=[O:13].[CH3:57][C:58]#[N:59].[Cs+:55].[Cs+:56]>>[CH2:1]([CH2:2][CH3:3])[n:4]1[c:5](=[O:30])[n:6]([CH2:27][CH2:28][CH3:29])[c:7]2[n:8][c:9](-[c:22]3[cH:23][n:24][n:25]([CH2:32][C:33](=[O:34])[CH:35]4[CH2:36][C:37](=[O:50])[N:38]([c:40]5[cH:41][c:42]([C:46]([F:47])([F:48])[F:49])[cH:43][cH:44][cH:45]5)[CH2:39]4)[cH:26]3)[n:10]([CH2:14][O:15][CH2:16][CH2:17][Si:18]([CH3:19])([CH3:20])[CH3:21])[c:11]2[c:12]1=[O:13]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1d2040c4c1524d0799afa82ab280548a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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