Formic Acid → HCID 90408205, compound

Participants

Reaction Steps

A mixture of Example 2B (299 mg, 1.013 mmol) in formic acid (500 μL, 13.25 mmol) was stirred at 90° C. for 1 hour. The cooled mixture was diluted with ethyl acetate, washed with water and brine, dried over magnesium sulfate, filtered and concentrated. Purification by silica gel flash chromatography (Isco®, Redi-Sep® column) eluting with 80% ethyl acetate/hexane afforded the title compound. MS (ESI) m/e 306 (M+H)+.

Provenance & Evidence