Sodium Hydroxide → HCID 90408206, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of Example 22C (500 mg, 0.75 mmol) in tetrahydrofuran (5 mL) and methanol (3 mL) was added 1M sodium hydroxide (2.24 mL, 2.24 mmol) and the mixture was stirred at 50° C. overnight. The mixture was diluted with water, extracted with dichloromethane, dried over sodium sulfate, filtered, and concentrated to provide the title compound. LCMS: 531.2 (M+H)+.

Provenance & Evidence