Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 871098Generated: October 31, 2026

3-Fluorobenzyl bromide → 6-bromo-1-(3-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile

https://huagongshe.com/reaction/871098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluorobenzyl bromideHCID 68007—
Reactant6-bromo-1H-pyrrolo(2,3-b)pyridine-3-carbonitrileHCID 73012892—
Product6-bromo-1-(3-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrileHCID 90408480—

Reaction Steps

The title compound was prepared as described in Example 28A using 6-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile in place of 6-bromo-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile and using 1-(bromomethyl)-3-fluorobenzene in place of 4-(bromomethyl)tetrahydro-2H-pyran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969375B2
Source datasetuspto-grants-2015_03
ORD IDord-f83eb6eb411b4d3d845b5a8b9df60c5b
Source noteuspto-grants-2015_03