Phenyl chloroformate → phenyl 3-tert-butyl-1-isobutyl-1H-pyrazol-5-ylcarbamate

HRID 871735Notes

Reaction equation

HRID 871735 reaction equation
Cl.[C:2]([C:6]1[CH:10]=[C:9]([NH2:11])[N:8]([CH2:12][CH:13]([CH3:15])[CH3:14])[N:7]=1)([CH3:5])([CH3:4])[CH3:3].Cl[C:17]([O:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:18]>>[C:2]([C:6]1[CH:10]=[C:9]([NH:11][C:17](=[O:18])[O:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[N:8]([CH2:12][CH:13]([CH3:15])[CH3:14])[N:7]=1)([CH3:5])([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 15891Phenyl chloroformateHCID 66876294HCID 66876294, compound

Product 1

HCID 66876741phenyl 3-tert-butyl-1-isobutyl-1H-pyrazol-5-ylcarbamate

Procedure

Following the procedure described for Example 330A Step 2, reaction of 3-tert-butyl-1-isobutyl-1H-pyrazol-5-amine hydrochloride with phenyl chloroformate, afforded phenyl 3-tert-butyl-1-isobutyl-1H-pyrazol-5-ylcarbamate which was used in the subsequent step.

Sources & evidence

ORD record
ord-a87a467636c64035973c3f97c1fd5ed6
Source dataset
uspto-grants-2015_03
Patent number
US08969587B2

Reaction notes

Loading…