化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Octanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Levofloxacin | HCID 149096 | — |
| 反応物 | Sodium octanoate | HCID 23664772 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Octanoate | HCID 119389 | — |
| 生成物 | Levofloxacin | HCID 149096 | — |
反応手順
One gram of sodium octanoate and one gram of levofloxacin were dissolved in 100 ml water. The pH was slowly adjusted to 6.0 by the addition of 1 M HCl. As the pH decreased, levofloxacin became protonated formed an insoluble HIP with the negatively charged octanoate. The precipitate was gathered by filtration to remove excess levofloxacin, dissolved sodium octanoate/octanoic acid, and salt. The sample was lyophilized overnight.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08974814B2 |
| 出典データセット | uspto-grants-2015_03 |
| ORD ID | ord-3c6fcf879372438aa17574c118390070 |
| 出典メモ | uspto-grants-2015_03 |