Chloroethane → HCID 70926147, compound

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Reaction Steps

To a solution of 0.05 g (0.13 mmol) of the product prepared in step 15.6 in 2.5 mL of methanol is added 0.20 mL (0.4 mmol) of 2.0 M hydrochloric ether. The mixture is stirred for 5 minutes at room temperature and then evaporated to dryness. The residue is purified by preparative HPLC. The fraction corresponding to the expected pure product is evaporated to dryness under then taken up in methanol. Ether is added and the solid is drained by suction and dried in an oven under vacuum. 0.031 g of the expected product is obtained. Yield (dihydrochloride)=49%. m.p.=208-210°C. (decomposition). M+H+=408.

Provenance & Evidence