Hydrochloric Acid → HCID 70926616, compound

Participants

Reaction Steps

A solution of 0.70 g (1.22 mmol) of the product prepared in step 17.4 in 17 mL of methanol is cooled on an ice bath, and 0.91 mL (3.65 mmol) of a 4N solution of hydrogen chloride in dioxane is added. The mixture is stirred for 30 minutes at room temperature and is then poured into ether. The solid is drained by suction, rinsed with pentane and dried in an oven under vacuum. 0.64 g of the expected product is finally obtained in the form of a white solid. Yield (dihydrochloride)=91%. m.p.>260°C. M+H+=578

Provenance & Evidence