Ethanol → 6-Amino-2-(4-chloro-2-fluoro-3-methoxyphenyl)-5-ethyl-pyrimidine-4-carboxylic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:14]2[c:15]([F:23])[c:16]([O:21][CH3:22])[c:17]([Cl:20])[cH:18][cH:19]2)[n:8][c:9]([NH2:13])[c:10]1[CH:11]=[CH2:12].[CH3:26][CH2:27][OH:28].[H:24][H:25].[OH-:29].[OH-:31].[Pd+2:30]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7](-[c:14]2[c:15]([F:23])[c:16]([O:21][CH3:22])[c:17]([Cl:20])[cH:18][cH:19]2)[n:8][c:9]([NH2:13])[c:10]1[CH2:11][CH3:12]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-93359e6e2cec4dea9c965712942eb1bf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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