N-bromobutanimide → HCID 59494311, compound

Participants

Reaction Steps

N-Bromosuccinimide (978 mg) was added to a solution of [7-(3-methoxypropoxy)-1-benzofuran-5-yl]methanol (1.18 g) in dichloromethane (30 ml) under ice-cooling and the mixture was stirred at the same temperature for 10 minutes. The reaction mixture was concentrated in vacuo and the resulted residue was purified with a silica gel column chromatography (eluting solvent: n-hexane/ethyl acetate=1/1) to give [4-bromo-7-(3-methoxypropoxy)-1-benzofuran-5-yl]methanol (1.46 g) as a colorless oil.

Provenance & Evidence