4-Chloro-3,5-dinitrobenzotrifluoride → HCID 59293622, compound

HRID 872079Notes

Reaction equation

HRID 872079 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:12][CH2:11][C@@H:10]([OH:13])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl[C:15]1[C:20]([N+:21]([O-:23])=[O:22])=[CH:19][C:18]([C:24]([F:27])([F:26])[F:25])=[CH:17][C:16]=1[N+:28]([O-:30])=[O:29]>>[C:1]([O:5][C:6]([N:8]1[CH2:12][CH2:11][C@@H:10]([O:13][C:15]2[C:16]([N+:28]([O-:30])=[O:29])=[CH:17][C:18]([C:24]([F:27])([F:25])[F:26])=[CH:19][C:20]=2[N+:21]([O-:23])=[O:22])[CH2:9]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 98094-Chloro-3,5-dinitrobenzotrifluorideHCID 6544479tert-Butyl (3R)-3-hydroxypyrrolidine-1-carboxylate

Product 1

HCID 59293622HCID 59293622, compound

Procedure

deprotonating (R)-3-Hydroxypyrrolidine-1-carboxylic acid tert-butyl ester and further reacting the resultant compound with 2-chloro-1,3-dinitro-5-trifluoromethylbenzene to form (R)-3-(2,6-dinitro-4-trifluoromethylphenoxy)pyrrolidine-1-carboxylic acid tert-butyl ester;

Sources & evidence

ORD record
ord-8843ae05fa7f42d3bbfa7921ebb6759e
Source dataset
uspto-grants-2015_03
Patent number
US08975262B2

Reaction notes

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