HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methanesulfonyl)phenylboronic acid → (R)-4-[5-(4-Methanesulfonyl-phenyl)-2,3-dihydro-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methanesulfonyl)phenylboronic acid | HCID 2734364 | — |
| Reactant | (R)-4-(5-chloro-2,3-dihydro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid tert-butyl ester | HCID 86675682 | — |
| Product | (R)-4-[5-(4-Methanesulfonyl-phenyl)-2,3-dihydro-furo[2,3-c]pyridin-2-yl]-piperidine-1-carboxylic acid tert-butyl ester | HCID 71208264 | — |
Reaction Steps
The title compound is prepared from (R)-4-(5-chloro-2,3-dihydro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid tert-butyl ester and 4-(methylsulfonyl)-phenylboronic acid following a procedure analogous to that described for Intermediate 6. Mass spectrum (ESI+): m/z=459 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975277B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-49e86533bd9b4422a6faf16d95a4cd3e |
| Source note | uspto-grants-2015_03 |