HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminopyridine → 3-Chloro-N-4-pyridinylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminopyridine | HCID 1727 | — |
| Reactant | Benzoyl chloride, 3-chloro- | HCID 69252 | — |
| Product | 3-Chloro-N-4-pyridinylbenzamide | HCID 849128 | 52% |
Reaction Steps
Employing 0.18 g (1.9 mmol) of 4-amino-pyridine and 0.51 g, (2.9 mmol) of 3-chlorobenzoyl chloride in the procedure described above and elution with CHCl3/MeOH/Et3N (9.8:0.1:0.1) resulted in white crystals (52% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975288B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-d226ed2f36dd41f1b3056d47611bcb15 |
| Source note | uspto-grants-2015_03 |