Iodine → 2,2'-Dithiobis-3a,7a-dihydro-1H-benzimidazole

HRID 872371Notes

Reaction equation

HRID 872371 reaction equation
[SH:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[OH-].[Na+].II>C(O)C>[N:3]1[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[NH:6][C:2]=1[S:1][S:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

5

Reactant 3

HCID 807IodineHCID 14798Sodium HydroxideHCID 178527775HCID 178527775, compound

Product 1

HCID 2349542,2'-Dithiobis-3a,7a-dihydro-1H-benzimidazole

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution prepared from 10.0 g 2-mercaptobenzoimidazole, 88 g ethanol and 6.68 g 40% aqueous NaOH was mixed with a solution of 8.54 g iodine in 79 g of ethanol. The resulting mixture was filtered, and the collected product was washed with ethanol and dried under vacuum at 70° C.

Workup

  1. filtrationThe resulting mixture was filtered
  2. washthe collected product was washed with ethanol
  3. customdried under vacuum at 70° C.

Sources & evidence

ORD record
ord-f6910c5f729846b6bab48b34b9f76f55
Source dataset
uspto-grants-2015_03
Patent number
US08975316B2

Reaction notes

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