Iodine → 1,3,4-Thiadiazol-2-amine, 5,5'-dithiobis-

HRID 872372Notes

Reaction equation

HRID 872372 reaction equation
[NH2:1][C:2]1[S:3][C:4]([SH:7])=[N:5][N:6]=1.[OH-].[Na+].II>C(O)C>[NH2:1][C:2]1[S:3][C:4]([S:7][S:7][C:4]2[S:3][C:2]([NH2:1])=[N:6][N:5]=2)=[N:5][N:6]=1

Participants

5

Reactant 3

HCID 807IodineHCID 14798Sodium HydroxideHCID 178509208HCID 178509208, compound

Product 1

HCID 2160081,3,4-Thiadiazol-2-amine, 5,5'-dithiobis-

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution prepared from 10.0 g 2-amino-1,3,4-thiadiazole-5-thiol, 81 g ethanol and 7.78 g 40% aqueous NaOH was mixed with a solution of 9.48 g iodine in 75 g of ethanol. The resulting mixture was filtered, and the collected product was washed with ethanol and dried under vacuum at 70° C.

Workup

  1. filtrationThe resulting mixture was filtered
  2. washthe collected product was washed with ethanol
  3. customdried under vacuum at 70° C.

Sources & evidence

ORD record
ord-a79897e33e77402bab1e65e4131e3508
Source dataset
uspto-grants-2015_03
Patent number
US08975316B2

Reaction notes

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