Propionic Acid → 3,3-Bis(vinyloxymethyl)oxetane

Participants

Reaction Conditions

Reaction Steps

A mixture (280 ml) of 24.9 g (0.23 mol) of sodium carbonate with toluene was raised in temperature to 95° C., 1.4 g of propionic acid was added, and, while maintaining the temperature at 95° C., 16 g of vinyl acetate was added dropwise, and 15 minutes later, 1.27 g (1.9 mmol) of di-μ-chlorobis(1,5-cyclooctadiene)diiridium(I) [Ir(cod)Cl]2 was further added. Next, 40 g (0.19 mol) of oxetane-3,3-dimethanol was added dropwise over 3 hours for a reaction. After the completion of the dropwise addition and subsequent stirring for 1 hour, the reaction mixture was analyzed by gas chromatography and found that there were formed 3,3-bis(vinyloxymethyl)oxetane represented by the following formula in a yield of 90% and (3-vinyloxymethyloxetan-3-yl)methanol in a yield of 2%. The reaction mixture was purified by distillation and thereby yielded 31 g of 3,3-bis(vinyloxymethyl)oxetane with a purity of 99%.

Provenance & Evidence