HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Boc-(R)-(+)-2-amino-1-butanol → HCID 67171953, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Boc-(R)-(+)-2-amino-1-butanol | HCID 11435422 | — |
| Reactant | HCID 178422100 | HCID 178422100 | — |
| Product | HCID 67171953 | HCID 67171953 | 56.5% |
Reaction Steps
(R)-4-(1-(2-aminobutyl)-1H-pyrazol-3-yl)-2-chloro-3-methylbenzonitrile was prepared using the method of Example 99 starting from 2-chloro-3-methyl-4-(1H-pyrazol-3-yl)benzonitrile (2.0 g, 9.19 mmol) and (R)-tert-butyl 1-hydroxybutan-2-ylcarbamate (3.48 g, 18.38 mmol). Yield 56.5%. m/z [288.8+1].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975254B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-c2dca2f69c76493081a1c73790b756e2 |
| Source note | uspto-grants-2015_03 |