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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 872774Generated: October 30, 2026

Sodium Hydroxide → 3-Isopropyl-1,2,4-oxadiazole-5-carboxylic acid

https://huagongshe.com/reaction/872774

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant3-Isopropyl-[1,2,4]oxadiazole-5-carboxylic acid ethyl esterHCID 53404637—
Product3-Isopropyl-1,2,4-oxadiazole-5-carboxylic acidHCID 23201026—

Reaction Steps

The title compound was prepared from ethyl 3-isopropyl-1,2,4-oxadiazole-5-carboxylate (0.4 g, 2.17 mmol) and sodium hydroxide solution (6 mL) using the method of Example 225(b). Yield 0.25 g. 1H NMR (400 MHz; D2O): δ 1.33 (d, 6H), 3.17 (m, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975254B2
Source datasetuspto-grants-2015_03
ORD IDord-f0e7d08480b54797811c2415ca9b66f5
Source noteuspto-grants-2015_03