Sodium Hydroxide → HCID 7144511, compound

HRID 872783Notes

Reaction equation

HRID 872783 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][C:8]2[O:12][N:11]=[C:10]([C:13]([O:15]CC)=[O:14])[CH:9]=2)[CH2:3][CH2:2]1.[OH-].[Na+]>>[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][C:8]2[O:12][N:11]=[C:10]([C:13]([OH:15])=[O:14])[CH:9]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 23006302Ethyl 5-(morpholinomethyl)isoxazole-3-carboxylate

Product 1

HCID 7144511HCID 7144511, compound

Procedure

The title compound was prepared from ethyl 5-(morpholinomethyl)isoxazole-3-carboxylate (0.2 g, 0.85 mmol) and sodium hydroxide solution (2 mL) using the method of Example 225(b). Yield 0.25 g. 1H NMR (400 MHz; D2O): δ 3.46 (m, 4H), 3.99 (m, 4H), 4.72 (s, 2H), 7.10 (m, 1H).

Sources & evidence

ORD record
ord-70cc39bf48a04db984dd7555b8b052be
Source dataset
uspto-grants-2015_03
Patent number
US08975254B2

Reaction notes

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