3,4,5-Trifluorobenzaldehyde → 3,5-Difluoro-4-((6-(trifluoromethyl)-3-pyridinyl)oxy)benzaldehyde

HRID 873042Notes

Reaction equation

HRID 873042 reaction equation
[F:1][C:2]([F:11])([F:10])[C:3]1[N:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.[F:12][C:13]1[CH:14]=[C:15]([CH:18]=[C:19]([F:22])[C:20]=1F)[CH:16]=[O:17]>>[F:12][C:13]1[CH:14]=[C:15]([CH:18]=[C:19]([F:22])[C:20]=1[O:9][C:6]1[CH:7]=[N:8][C:3]([C:2]([F:1])([F:10])[F:11])=[CH:4][CH:5]=1)[CH:16]=[O:17]

Participants

3

Reactant 2

HCID 27769543,4,5-TrifluorobenzaldehydeHCID 27833885-Hydroxy-2-(trifluoromethyl)pyridine

Product 1

HCID 866763653,5-Difluoro-4-((6-(trifluoromethyl)-3-pyridinyl)oxy)benzaldehyde

Procedure

The title compound was prepared by a procedure similar to those described for D4 starting from 6-(trifluoromethyl)3-pyridinol and 3,4,5-trifluorobenzaldehyde.

Sources & evidence

ORD record
ord-f5f6207e6aa744258438bfe75b5a56dd
Source dataset
uspto-grants-2015_03
Patent number
US08975400B2

Reaction notes

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