HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → tert-butyl 7-((3-cyano-4-(3-(trifluoromethyl)phenoxy)benzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 5-(Hydroxymethyl)-2-(3-(trifluoromethyl)phenoxy)benzonitrile | HCID 66825436 | — |
| Reactant | Tert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-C]pyrimidine-1(5H)-carboxylate | HCID 71743561 | — |
| Product | tert-butyl 7-((3-cyano-4-(3-(trifluoromethyl)phenoxy)benzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate | HCID 71241034 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E1 starting from sodium hydride and 5-(hydroxymethyl)-2-(3-(trifluoromethyl)phenoxy)benzonitrile and tert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975400B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-3aedde6e17304487b687bfc91dd47e15 |
| Source note | uspto-grants-2015_03 |