HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → tert-butyl 7-((4-(3-chloro-4-fluorophenoxy)-3-cyanobenzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-(3-Chloro-4-fluorophenoxy)-5-(hydroxymethyl)benzonitrile | HCID 71236832 | — |
| Reactant | Tert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-C]pyrimidine-1(5H)-carboxylate | HCID 71743561 | — |
| Product | tert-butyl 7-((4-(3-chloro-4-fluorophenoxy)-3-cyanobenzyl)oxy)-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate | HCID 86724167 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E1 starting from NaH, 2-(3-chloro-4-fluorophenoxy)-5-(hydroxymethy)benzonitrile and tert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1 (5H)-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975400B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-ee9cbe3f4266454f8d045a166b1d0ffb |
| Source note | uspto-grants-2015_03 |