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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 873077Generated: October 30, 2026

Sodium hydride → HCID 71243717, compound

https://huagongshe.com/reaction/873077

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
ReactantHCID 71239623HCID 71239623—
ReactantTert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-C]pyrimidine-1(5H)-carboxylateHCID 71743561—
ProductHCID 71243717HCID 71243717—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E1 starting from NaH, 5-(hydroxymethyl)-2-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzonitrile and tert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-c]pyrimidine-1(5H)-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975400B2
Source datasetuspto-grants-2015_03
ORD IDord-67d16901439d4f7bb0ea740cf8e920e9
Source noteuspto-grants-2015_03