4-Fluoro-3-(trifluoromethyl)benzaldehyde → 3-(4-Formyl-2-(trifluoromethyl)phenoxy)-5-(trifluoromethyl)benzonitrile

HRID 873088Notes

Reaction equation

HRID 873088 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:9]=1)[C:5]#[N:6].F[C:15]1[CH:22]=[CH:21][C:18]([CH:19]=[O:20])=[CH:17][C:16]=1[C:23]([F:26])([F:25])[F:24]>>[CH:19]([C:18]1[CH:21]=[CH:22][C:15]([O:1][C:2]2[CH:3]=[C:4]([CH:7]=[C:8]([C:10]([F:11])([F:12])[F:13])[CH:9]=2)[C:5]#[N:6])=[C:16]([C:23]([F:24])([F:25])[F:26])[CH:17]=1)=[O:20]

Participants

3

Reactant 2

HCID 5222694-Fluoro-3-(trifluoromethyl)benzaldehydeHCID 534131963-Hydroxy-5-(trifluoromethyl)benzonitrile

Product 1

HCID 867241733-(4-Formyl-2-(trifluoromethyl)phenoxy)-5-(trifluoromethyl)benzonitrile

Procedure

The title compound was prepared by a procedure similar to that described for D4 starting from 3-hydroxy-5-(trifluoromethyl)benzonitrile and 4-fluoro-3-(trifluoromethyl)benzaldehyde.

Sources & evidence

ORD record
ord-0af7f86c307f42a18cf07e66adf2e788
Source dataset
uspto-grants-2015_03
Patent number
US08975400B2

Reaction notes

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