3,4-Difluorobenzaldehyde → 3-Fluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzaldehyde

HRID 873098Notes

Reaction equation

HRID 873098 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1F)[CH:5]=[O:6].[F:11][C:12]([F:21])([F:20])[C:13]1[CH:18]=[C:17]([OH:19])[CH:16]=[CH:15][N:14]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:19][C:17]1[CH:16]=[CH:15][N:14]=[C:13]([C:12]([F:21])([F:11])[F:20])[CH:18]=1)[CH:5]=[O:6]

Participants

3

Reactant 2

HCID 5880883,4-DifluorobenzaldehydeHCID 178516505HCID 178516505, compound

Product 1

HCID 867241713-Fluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzaldehyde

Procedure

The title compound was prepared by a procedure similar to that described for D4 starting from 3,4-difluorobenzaldehyde and 2-(trifluoromethyl)pyridin-4-ol.

Sources & evidence

ORD record
ord-3a318601487f4b559070310c1e8ba7e6
Source dataset
uspto-grants-2015_03
Patent number
US08975400B2

Reaction notes

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