3-(Trifluoromethyl)phenol → HCID 71239727, compound

HRID 873105Notes

Reaction equation

HRID 873105 reaction equation
[Br:1][C:2]1[C:3](Cl)=[N:4][CH:5]=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8].[F:13][C:14]([F:23])([F:22])[C:15]1[CH:16]=[C:17]([OH:21])[CH:18]=[CH:19][CH:20]=1>>[Br:1][C:2]1[C:3]([O:21][C:17]2[CH:18]=[CH:19][CH:20]=[C:15]([C:14]([F:13])([F:22])[F:23])[CH:16]=2)=[N:4][CH:5]=[C:6]([CH:11]=1)[C:7]([O:9][CH3:10])=[O:8]

Participants

3

Reactant 2

HCID 73763-(Trifluoromethyl)phenolHCID 2764313Methyl 5-bromo-6-chloronicotinate

Product 1

HCID 71239727HCID 71239727, compound

Procedure

The title compound was prepared by a procedure similar to that described for D4 starting from methyl 5-bromo-6-chloronicotinate and 3-(trifluoromethyl)phenol.

Sources & evidence

ORD record
ord-b9285cdfb0534c4f9014fb4119eec98f
Source dataset
uspto-grants-2015_03
Patent number
US08975400B2

Reaction notes

Loading…