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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 873108Generated: October 31, 2026

Sodium hydride → HCID 71243764, compound

https://huagongshe.com/reaction/873108

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
ReactantHCID 71239622HCID 71239622—
ReactantTert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo[1,2-C]pyrimidine-1(5H)-carboxylateHCID 71743561—
ProductHCID 71243764HCID 71243764—

Reaction Steps

The title compound was prepared by a procedure similar to that described for E1 starting from NaH, 5-(hydroxymethyl)-2-(3-(trifluoromethyl)phenoxy)nicotinonitrile and tert-butyl 7-chloro-5-oxo-2,3-dihydroimidazo-[1,2-c]pyrimidine-1(5H)-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975400B2
Source datasetuspto-grants-2015_03
ORD IDord-9354f893243e48f79363783717db8213
Source noteuspto-grants-2015_03