HCID 621706, compound → HCID 67958322, compound

HRID 873146Notes

Reaction equation

HRID 873146 reaction equation
BrP(C)(C1C=CC=CC=1)(C1C=CC=CC=1)[C:3]1C=CC=CC=1.CC([O-])(C)C.[K+].[F:28][C:29]1[CH:30]=[C:31]([CH:42]=[CH:43][C:44]=1[F:45])[O:32][C:33]1[CH:40]=[CH:39][C:36]([CH:37]=O)=[CH:35][C:34]=1[F:41]>>[F:28][C:29]1[CH:30]=[C:31]([CH:42]=[CH:43][C:44]=1[F:45])[O:32][C:33]1[CH:40]=[CH:39][C:36]([CH:37]=[CH2:3])=[CH:35][C:34]=1[F:41]

Participants

4

Reactant 3

HCID 621706HCID 621706, compoundHCID 23665647Potassium tert-butoxideHCID 43554841HCID 43554841, compound

Product 1

HCID 67958322HCID 67958322, compound

Procedure

The title compound was prepared by a procedure similar to that described for D162 starting from bromo(methyl)triphenylphosphorane, potassium 2-methylpropan-2-olate and 4-(3,4-difluorophenoxy)-3-fluorobenzaldehyde.

Sources & evidence

ORD record
ord-945fa6f7a7d04c84af288d199599cf90
Source dataset
uspto-grants-2015_03
Patent number
US08975400B2

Reaction notes

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