Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 873173Generated: October 25, 2026

(3,5-Difluoro-4-((6-(trifluoromethyl)-3-pyridinyl)oxy)phenyl)methanol → 7-((3,5-difluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)benzyl)oxy)-1-methyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one

https://huagongshe.com/reaction/873173

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3,5-Difluoro-4-((6-(trifluoromethyl)-3-pyridinyl)oxy)phenyl)methanolHCID 66825487—
Reactant7-Chloro-1-methyl-2,3-dihydroimidazo[1,2-C]pyrimidin-5(1H)-oneHCID 71743458—
Product7-((3,5-difluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)benzyl)oxy)-1-methyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-oneHCID 71240847—

Reaction Steps

The title compound was prepared by a procedure similar to those described for E1 starting from 7-chloro-1-methyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one and (3,5-difluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)phenyl)methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08975400B2
Source datasetuspto-grants-2015_03
ORD IDord-732dde04041d43ed8e81777335edf4b6
Source noteuspto-grants-2015_03