HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 71241189, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 71239878 | HCID 71239878 | — |
| Reactant | 7-Chloro-1-methyl-2,3-dihydroimidazo[1,2-C]pyrimidin-5(1H)-one | HCID 71743458 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 71241189 | HCID 71241189 | — |
Reaction Steps
Prepared in a manner similar to that described for E1 using (3,5-difluoro-4-((5-(trifluoromethyl)pyridin-3-yl)oxy)phenyl)methanol (250 mg, 0.819 mmol) in DMF (5 mL), sodium hydride (59.0 mg, 2.46 mmol) and 7-chloro-1-methyl-2,3-dihydroi-midazo[1,2-c]pyrimidin-5(1H)-one (152 mg, 0.819 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08975400B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-2a611b91b208461fa8d36c82f239bf33 |
| Source note | uspto-grants-2015_03 |