反应详情

(3-Formyl-4-methoxyphenyl)boronic acid (5.30 g, 29.5 mmol) and 5,5-dimethylcyclohexane-1,3-dione (8.26 g, 58.9 mmol) were added to a suspension of dodecylbenzenesulfonic acid (0.96 g, 2.94 mmol) in water (196 ml) at room temperature, and the mixture thus obtained was then stirred under heating to reflux for 5 hours. After air-cooling, a solid was collected from the reaction solution by filtration. The solid thus obtained was suspended in ethanol, and the solution thus obtained was then stirred under heating to reflux. After air-cooling, the solvent was distilled away from the reaction solution under reduced pressure. Diethyl ether was added to the residue thus obtained, and the solid thus generated was collected by filtration and was then dried to obtain the title compound (7.99 g, yield: 64%).

1. customthe mixture thus obtained
2. temperatureunder heating
3. temperatureto reflux for 5 hours
4. temperatureAfter air-cooling
5. filtrationa solid was collected from the reaction solution by filtration
6. customThe solid thus obtained
7. customthe solution thus obtained
8. stirringwas then stirred
9. temperatureunder heating to reflux
10. temperatureAfter air-cooling
11. distillationthe solvent was distilled away from the reaction solution under reduced pressure
12. additionDiethyl ether was added to the residue
13. customthus obtained
14. filtrationthe solid thus generated was collected by filtration
15. customwas then dried