Diethyl Ether → HCID 117700852, compound

Participants

Reaction Steps

2-Methylpropan-2-amine (0.041 ml, 0.39 mmol) was added to a suspension of the 6-[4-methoxy-2-methyl-3-(3,3,6,6-tetramethyl-1,8-dioxo-2,3,4,5,6,7,8,9-octahydro-1H-xanthen-9-yl)phenyl]-4-methyl-N-(methylsulfonyl)pyridine-2-carboxamide produced in Example 40 (118 mg, 0.19 mmol) in ethanol (1.2 ml) at room temperature, and the mixture thus obtained was then stirred at the same temperature as above for 1 hour. Thereafter, diethyl ether was added to the reaction solution, and the solid thus generated was collected by filtration and was then dried to obtain the title compound (111 mg, yield: 84%).

Provenance & Evidence