HCID 86702061, compound → HCID 86702060, compound

HRID 873579Notes

Reaction equation

HRID 873579 reaction equation
Cl[C:2]1[N:7]=[N:6][C:5]([N:8]2[CH2:13][CH2:12][CH:11]([C:14]([NH:16][C:17]3[CH:22]=[CH:21][C:20]([CH:23]4[CH2:28][CH2:27][N:26]([C:29]([O:31][C:32]([CH3:35])([CH3:34])[CH3:33])=[O:30])[CH2:25][CH2:24]4)=[CH:19][CH:18]=3)=[O:15])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.ClC1N=NC(N2CC(C(NC3C=CC(C4CCN(C([O-])=O)CC4)=CC=3)=O)C2)=CC=1>>[N:7]1[CH:2]=[CH:3][CH:4]=[C:5]([N:8]2[CH2:9][CH2:10][CH:11]([C:14]([NH:16][C:17]3[CH:22]=[CH:21][C:20]([CH:23]4[CH2:28][CH2:27][N:26]([C:29]([O:31][C:32]([CH3:35])([CH3:34])[CH3:33])=[O:30])[CH2:25][CH2:24]4)=[CH:19][CH:18]=3)=[O:15])[CH2:12][CH2:13]2)[N:6]=1

Participants

3

Reactant 2

HCID 86702061HCID 86702061, compoundHCID 86702062HCID 86702062, compound

Product 1

HCID 86702060HCID 86702060, compound

Procedure

The title compound was prepared as described in Example 147B, tert-butyl 4-(4-(1-(6-chloropyridazin-3-yl)piperidine-4-carboxamido)phenyl)piperidine-1-carboxylate for 4-(4-(1-(6-chloropyridazin-3-yl)azetidine-3-carboxamido)phenyl)piperidine-1-carboxylate.

Sources & evidence

ORD record
ord-145fa5f2e9754fef8d7a579fc4f9399b
Source dataset
uspto-grants-2015_03
Patent number
US08975398B2

Reaction notes

Loading…